Mario Andretti won the 1969 Indianapolis 500, he and members of his family have come close in 68 total starts, but have not managed another win at Indy. Mario once said that "Lady Luck" seemed to be against him at the Indianapolis Speedway. Some started calling the shutout streak the "Andretti Curse", it has also been referred to as the "Andretti Luck."
In 1969, Mario dominated the second half of the race, maintaining a full lap lead late in the race, and won comfortably.
In 1981, Mario finished 8 seconds behind Bobbi Unser, who was declared the unofficial winner. The following day Unser was penalized one lap for passing cars under a caution flag, and Mario was declared the winner. Unser and his car owner Roger Penske appealed the race stewards' decision. USAC overturned the one lap penalty four months later, restoring Unser as the winner.
In 1987, Mario led 170 of 177 laps and built up such a huge lead that he decided to back off a little. The reduced revs, however, created a harmonic imbalance in his Ilmor/Chevrolet engine that led to a broken valve spring with 20 laps to go.
In 1991, son Michael took the lead on lap 188, passing Rick Mears on the outside on turn one. One lap later, Mears took the lead with the same move, and began pulling away. A caution resulted when Mario coasted to a stop at the entrance to pit row, and their was a brief controversy as some suggested that this was a deliberate move to help his son. But on the restart, Mears again pulled away to win his 4th Indy 500, and the controversy rightly fizzled. Mario's nephew, John, posted his best finish at Indy: 5th, three laps down.
Mario would call the day of the 1992 race the worst of his life. After experiencing some mechanical troubles early, Mario crashed on a restart in turn 4; he suffered some broken toes and was flown to a hospital in downtown Indianapolis. Not long after this, Mario's son Jeff shattered both of his legs in a terrible crash, and was also taken to the hospital. Meanwhile, Michael was dominating the race, leading 160 of 189 laps, and looked poised to win, only to have his fuel pump fail with 11 laps to go.
In 2005, there was some talk of the "curse" being broken as Michael wins the race as a team owner, the driver being Dan Wheldon.
In 2006, Michael's son Marco is poised to win the race as a rookie, leading most of the final lap, until Sam Hornish passes him just before reaching the finish line. Michael, back in the car to race with his son, finished 3rd.
In 2007, Michael would win again as a team owner, with driver Dario Franchitti.
Marco would post third place finishes in 2008, 2010 and 2014. Marco has been in the running late in several races, but has not been able to break through and win.